Surgical site infections (SSIs) are caused by many factors # some are controllable, while others are uncontrollable. Suture selection provides an opportunity to address a known risk factor for infection # bacterial colonization of the suture. Percutaneous sutures create a conduit for bacteria to enter the wound. Additionally, like all foreign bodies, when implanted, sutures are rapidly coated with tissue protein, creating sites for bacterial colonization. This colonization can lead to biofilm formation, which can increase the difficulty of treating an infection even in the presence of antibiotics. Plus Antibacterial Solutions are the only commercially available sutures with antibacterial protection. -Proven in vitro to kill bacteria and inhibit bacterial colonization of the suture for 7 days or more137,138,146 -Effective against pathogens commonly associated with surgical site infections, including:- -Staphylococcus aureus. -Staphylococcus epidermidis. -Methicillin-resistant Staphylococcus aureus (MRSA). -Methicillin-resistant Staphylococcus epidermidis (MRSE). -Escherichia coli. -Klebsiella pneumoniae.