Additional Information

Description

Ketamine 50 mg/mL, in a 10 mL multiple-dose vial, is a powerful anesthetic and analgesic agent used primarily in medical settings. It belongs to the class of dissociative anesthetics and functions as an NMDA receptor antagonist. Ketamine is commonly used for the induction and maintenance of anesthesia during surgical procedures, especially in patients with contraindications to other anesthetics.

The drug exerts its effects by inhibiting the action of excitatory neurotransmitters, specifically glutamate, at the NMDA receptor sites in the brain. This results in analgesia, amnesia, and sedation, making it useful in both minor and major surgeries. Ketamine’s unique mechanism allows it to provide anesthesia without significantly depressing the respiratory system.

In addition to its anesthetic properties, ketamine has demonstrated efficacy in managing acute pain, including in emergency departments and trauma care. It has also been explored for its potential in treating treatment-resistant depression and post-traumatic stress disorder (PTSD).