Additional Information

Description

Dacarbazine 200 mg/20 mL is a sterile injectable solution used as an antineoplastic agent for the treatment of various types of cancer. It belongs to the class of alkylating agents and works by interfering with the DNA synthesis of rapidly dividing cancer cells. This cytotoxic action helps inhibit tumor growth, making it an effective option for specific malignancies.

The product is supplied in a box containing 10 single-use vials, each containing 200 mg of dacarbazine dissolved in 20 mL of solution. Dacarbazine is commonly utilized in the treatment of metastatic melanoma, Hodgkin's lymphoma, and sarcomas. It is often combined with other chemotherapeutic agents to enhance efficacy. The formulation is designed for intravenous administration.

Dacarbazine exhibits a unique mechanism of action by converting into active metabolites in the liver, which then alkylate the DNA, leading to cancer cell death. It has a half-life of approximately 5 hours and is excreted primarily through the kidneys. Supportive care during therapy is essential to manage potential side effects, including nausea, vomiting, myelosuppression, and liver toxicity.