Product Details

Tobramycin MDV 80mg/2mL

Manufacturer: Mylan

MFG#: 67457047322

NDC: 61314-0647-10

PID: 417785

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Additional Information

Product NameTobramycin Mdv 80 mg/2 mL
Drug ClassAminoglycoside Antibiotic
Generic Drug NameTobramycin Sulfate
Mechanism of ActionBinds irreversibly to the 30S ribosomal subunit, inhibiting bacterial protein synthesis and causing cell death.
Strength40 mg/mL
Volume2 mL
Onset of ActionRapid, within 30-60 minutes following intravenous administration
Duration of Action6-12 hours, depending on renal function and dosage
Side EffectsNephrotoxicity, ototoxicity, neuromuscular blockade, and injection site irritation
Pregnancy CategoryCategory D: Risk to the fetus, use only if benefits outweigh risks
Resistance PotentialOveruse may lead to bacterial resistance; should only be used based on susceptibility testing
StorageStore at 20-25°C (68-77°F) and protect from light
UsesTreatment of serious Gram-negative bacterial infections, including septicemia, respiratory tract infections, and urinary tract infections.

Description

Tobramycin 80 mg/2 mL is an aminoglycoside antibiotic formulation used for the treatment of serious bacterial infections caused by Gram-negative organisms. It is particularly effective against Pseudomonas aeruginosa, Klebsiella species, and certain Enterobacteriaceae. The medication works by irreversibly binding to the 30S ribosomal subunit of bacterial cells, inhibiting protein synthesis and leading to bacterial cell death.

This injectable formulation is supplied in a 2 mL multiple-dose vial, with a concentration of 40 mg/mL. It is administered intramuscularly or intravenously by trained healthcare professionals and is used in conditions such as septicemia, respiratory tract infections, urinary tract infections, and intra-abdominal infections.

Tobramycin is generally well-tolerated but requires careful monitoring to minimize the risk of adverse effects, particularly nephrotoxicity and ototoxicity, which are dose- and duration-dependent. Baseline and periodic renal function tests and audiometric evaluations are recommended during therapy.

Frequently Asked Questions (FAQs)

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Tobramycin MDV 80mg/2mL is manufactured by Mylan.

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