Product Details

Levophed SDV 1mg/mL 4mL

Manufacturer: Hospira

MFG#: 00409-3375-04

NDC: 00409-3375-04

PID: 417665

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Additional Information

Product NameLevophed Sdv 1Mg/Ml 4Ml
Generic Drug NameNorepinephrine Bitartrate
Mechanism of ActionStimulates alpha-adrenergic receptors causing vasoconstriction, with minor beta-adrenergic effects
Strength1 mg/mL
Volume4 mL
TypeIntravenous
Dilution RequirementsMust be diluted in a dextrose-containing solution before administration
Onset of ActionRapid, typically within 1-2 minutes after IV administration
Duration of ActionShort, requiring continuous infusion to maintain effect
PackagingSupplied as single-dose 4 mL vials
Administration PrecautionsAdminister via central line to prevent tissue damage from extravasation
Side EffectsHypertension, bradycardia, arrhythmias, ischemia
ContraindicationsHypotension due to blood volume deficit without fluid resuscitation
UsesTreatment of acute hypotension, septic shock, and neurogenic shock

Description

Levophed (Norepinephrine Bitartrate) 1 mg/mL is a sterile, single-dose vial formulation used as a potent vasopressor to treat acute hypotension and shock. It is intended for intravenous administration and requires careful dilution before use. The drug acts by stimulating alpha-adrenergic receptors in vascular smooth muscle, leading to vasoconstriction and an increase in blood pressure.

This medication is primarily utilized in critical care settings for conditions such as septic shock, neurogenic shock, or hypotension unresponsive to fluid resuscitation. Its rapid onset of action and strong vasoconstrictive effects make it an essential treatment for life-threatening cardiovascular conditions. It is typically administered via a central line to reduce the risk of extravasation and related tissue damage.

Levophed is supplied in single-dose 4 mL vials containing 1 mg of norepinephrine per mL, free from preservatives. It must be diluted before administration in a dextrose-containing solution to prevent oxidation. The diluted solution should be protected from light and used within 24 hours.

Frequently Asked Questions (FAQs)

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Levophed SDV 1mg/mL 4mL is manufactured by Hospira.

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